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Solvent-Free L-Proline Catalyzed Condensation of Ethyl Cyanoacetate with Aldehydes.

✍ Scribed by Hossein A. Oskooie; Elham Roomizadeh; Majid M. Heravi


Publisher
John Wiley and Sons
Year
2006
Weight
16 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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ChemInform Abstract: Microwave Enhanced
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Microwave Enhanced Knoevenagel Condensation of Ethyl Cyanoacetate with Aldehydes. -The reaction rate of Knoevenagel condensation can be significantly enhanced by irradiating the reaction mixture with microwaves. -(KIM, S.-Y.

L-Proline Catalyzed Solvent-Free Knoeven
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## Abstract __L__‐Proline was utilized as an efficient organo‐catalyst for the environmentally benign synthesis of 3‐substituted coumarins by the Knoevenagel condensation of substituted 2‐hydroxybenzaldehydes with reactive methylene compounds under solvent free conditions.