Solvent-Free L-Proline Catalyzed Condensation of Ethyl Cyanoacetate with Aldehydes.
β Scribed by Hossein A. Oskooie; Elham Roomizadeh; Majid M. Heravi
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 16 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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β¦ Synopsis
Abstract
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Microwave Enhanced Knoevenagel Condensation of Ethyl Cyanoacetate with Aldehydes. -The reaction rate of Knoevenagel condensation can be significantly enhanced by irradiating the reaction mixture with microwaves. -(KIM, S.-Y.
## Abstract __L__βProline was utilized as an efficient organoβcatalyst for the environmentally benign synthesis of 3βsubstituted coumarins by the Knoevenagel condensation of substituted 2βhydroxybenzaldehydes with reactive methylene compounds under solvent free conditions.