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Solvent-Free Bromination of 1,3-Diketones and β-Keto Esters with NBS.

✍ Scribed by Igor Pravst; Marko Zupan; Stojan Stavber


Publisher
John Wiley and Sons
Year
2007
Weight
25 KB
Volume
38
Category
Article
ISSN
0931-7597

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## Abstract The N‐heterocyclic carbene‐catalyzed reaction of alkynyl aldehydes with 1,3‐keto esters or 1,3‐diketones has been studied. This protocol offers an entirely new, mild and atom‐economical access to highly functionalized 3,4‐dihydropyranones.