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Solvent Composition and Viscosity Effects on the Kinetics of CO Binding to Horse Myoglobin †

✍ Scribed by Kleinert, Thomas; Doster, Wolfgang; Leyser, Harald; Petry, Winfried; Schwarz, Veronika; Settles, Marcus


Book ID
127259851
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
237 KB
Volume
37
Category
Article
ISSN
0006-2960

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The kinetics of folding of the two forms of unfolded ribonuclease A have been measured as a function of solvent viscosity by adding either glycerol or sucrose. The aim is to find out if either reaction is rate limited by segmental motion whose rate depends on external friction. The fast folding rea