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Solvent- and catalyst-free reaction of (aminomethyl)phosphonates with epoxides: Synthesis of novel {[(2-hydroxyethyl)amino]methyl}phosphonates

โœ Scribed by Babak Kaboudin; Mina Sorbiun


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
110 KB
Volume
21
Category
Article
ISSN
1042-7163

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โœฆ Synopsis


Abstract

Uncatalyzed reaction of epoxides with (aminomethyl)phosphonates for the synthesis of novel {[(2โ€hydroxyethyl)amino]methyl}phosphonates is described. Treatment of (aminomethyl)phosphonates with epoxides without any catalyst and under solventโ€free conditions gives novel {[(2โ€hydroxyethyl)amino]methyl}phosphonates. Using this method, a series of {[(2โ€hydroxyethyl)amino]methyl}phosphonates was synthesized in good yields. ยฉ 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:284โ€“289, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20615


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