Solvent- and catalyst-free reaction of (aminomethyl)phosphonates with epoxides: Synthesis of novel {[(2-hydroxyethyl)amino]methyl}phosphonates
โ Scribed by Babak Kaboudin; Mina Sorbiun
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 110 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1042-7163
- DOI
- 10.1002/hc.20615
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โฆ Synopsis
Abstract
Uncatalyzed reaction of epoxides with (aminomethyl)phosphonates for the synthesis of novel {[(2โhydroxyethyl)amino]methyl}phosphonates is described. Treatment of (aminomethyl)phosphonates with epoxides without any catalyst and under solventโfree conditions gives novel {[(2โhydroxyethyl)amino]methyl}phosphonates. Using this method, a series of {[(2โhydroxyethyl)amino]methyl}phosphonates was synthesized in good yields. ยฉ 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:284โ289, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20615
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