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Solvation Free Energy of the Peptide Group: Its Model Dependence and Implications for the Additive-Transfer Free-Energy Model of Protein Stability

✍ Scribed by Tomar, Dheeraj S.; Asthagiri, D.; Weber, Valéry


Book ID
122348997
Publisher
Biophysical Society
Year
2013
Tongue
English
Weight
324 KB
Volume
105
Category
Article
ISSN
0006-3495

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## Abstract The generalized Born/surface area (GB/SA) continuum model for solvation free energy is a fast and accurate alternative to using discrete water molecules in molecular simulations of solvated systems. However, computational studies of large solvated molecular systems such as enzyme–ligand