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Solution Structure of Glutathione Bound to Human Glutathione Transferase P1-1: Comparison of NMR Measurements with the Crystal Structure †

✍ Scribed by Nicotra, Maria; Paci, Maurizio; Sette, Marco; Oakley, Aaron J.; Parker, Michael W.; Lo Bello, Mario; Caccuri, Anna Maria; Federici, Giorgio; Ricci, Giorgio


Book ID
127379034
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
83 KB
Volume
37
Category
Article
ISSN
0006-2960

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Molecular dynamics simulations of human
✍ Lorenzo Stella; Ernesto E. Di Iorio; Maria Nicotra; Giorgio Ricci 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 384 KB

We have investigated by molecular dynamics simulations the conformational fluctuations of the monomer of human apo-glutathione transferase P1-1. After attainment of steady-state dynamics, the structural fluctuations involve mainly the protein segments that participate also in the holo-apo transition