Solution structure of a small protein containing a fluorinated side chain in the core
β Scribed by Gabriel Cornilescu; Erik B. Hadley; Matthew G. Woll; John L. Markley; Samuel H. Gellman; Claudia C. Cornilescu
- Book ID
- 111752862
- Publisher
- Cold Spring Harbor Laboratory Press
- Year
- 2006
- Tongue
- English
- Weight
- 332 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0961-8368
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π SIMILAR VOLUMES
The peptide toxin bombolitin III [B(III)], originally isolated from bumblebee venom, has been shown to undergo a concentration-dependent conformational change from a random structure to an alpha-helix induced by aggregation. The aggregation process and the consequent folding results from a delicate
2 reacts with fluorosilanes, e.g. with F3SiC6H5, in the molar ratio 1 2 to give disubstituted ("monomeric") products containing an eight-membered ring. ['] Reaction in the molar ratio 1 : 1 leads to a derivative 4 of the novel bicyclic system 1,3,5,7-tetraaza-2,4,6,8,9-pentasilabicyclo[3.3.l]nonane