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Solution structure of a peptide fragment of human α–lactalbumin in trifluorethanol: a model for local structure in the molten globule

✍ Scribed by Lorna J Smith; Andrei T Alexandrescu; Maureen Pitkeathly; Christopher M Dobson


Book ID
114328650
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
928 KB
Volume
2
Category
Article
ISSN
0969-2126

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Solution structure of a peptide model of
✍ Stephen J. Demarest; Daniel P. Raleigh 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 373 KB 👁 1 views

Elucidating the properties of the denatured state of proteins under conditions relevant for their folding is a key factor in understanding the folding process. We show that a peptide corresponding to residues 111-120 of human ␣-lactalbumin has a pronounced propensity to adopt nonnative structure in