## Abstract The solution‐state conformations of __N__,__N′__,__N″__‐triacetyl chitotriose (**1**) and other potential chitinase inhibitors **2**–**4** were studied using a combination of NMR spectroscopy (NOESY) and molecular mechanics calculations. Determination solely of the global energy minimum
Solution-State Conformational Study of the Hevamine Inhibitor Allosamidin and Six Potential Inhibitor Analogues by NMR Spectroscopy and Molecular Modeling
✍ Scribed by Germer, Antje; Peter, Martin G.; Kleinpeter, Erich
- Book ID
- 115521115
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 311 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
KNI-272, a highly selective and potent HIV protease inhibitor containing allophenylnorstatine [(2S,3S)-3-amino-2-hydroxy-4-phenylbutyric acid], named Apns, has been studied in dimethylsulfoxide-d6 by NMR spectroscopy and simulated annealing calculations. 1H and 13C spectra showed the presence of two