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Solution state conformation and degradation of cyclopeptides containing an NGR motif

✍ Scribed by Anna K. Füzéry; Nikolett Mihala; Pál Szabó; András Perczel; Raffaella Giavazzi; Helga Süli-Vargha


Book ID
105360401
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
199 KB
Volume
11
Category
Article
ISSN
1075-2617

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Synthesis and conformational preferences
✍ Christine Hemmerlin; Manh Thong Cung; Guy Boussard 📂 Article 📅 2001 🏛 Elsevier Science 🌐 French ⚖ 145 KB

The aza-tripeptide Boc-Ala-AzPip-Ala-NHiPr (AzPip: 2-aza pipecolyl residue) was synthesized in seven steps using preferentially the diisopropylcarbodiimide/1-hydroxy-7-aza-benzotriazole (DIPCDI/AtOH) coupling method and via the Boc-AzPip-OBzl pivotal intermediate. Its crystal molecular structure is