𝔖 Bobbio Scriptorium
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Solution phase synthesis of the 14-residue peptaibol antibiotic trichovirin I

✍ Scribed by H. Brückner; A. Koza

Book ID
106220940
Publisher
Springer
Year
2003
Tongue
English
Weight
231 KB
Volume
24
Category
Article
ISSN
0939-4451

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## Abstract According to the earlier published synthesis of the C‐terminal nonapeptide of Trichovirin I 1B, Z‐Ser(^__t__^Bu)‐Val‐Aib‐Pro‐Aib‐Leu‐Aib‐Pro‐Leuol (**5**), the complete tetradecapeptide Z‐Aib‐Asn(Trt)‐Leu‐Aib‐Pro‐Ser(^__t__^Bu)‐Val‐Aib‐Pro‐Aib‐Leu‐Aib‐Pro‐Leuol (**11b**), a protected Tr

Characterization of a type of β-bend rib
Characterization of a type of β-bend ribbon spiral generated by the repeating (Xaa–Yaa–Aib–Pro) motif: The solution structure of harzianin HC IX, a 14-residue peptaibol forming voltage-dependent ion channels
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The three-dimensional solution structure of harzianin HC IX, a peptaibol antibiotic isolated from the fungus Trichoderma harzianum, was determined using CD, homonuclear, and heteronuclear two-dimensional nmr spectroscopy combined with molecular modeling. This 14residue peptide, Ac Aib 1 Asn 2 Leu 3