Solution-phase combinatorial synthesis via the olefin metathesis reaction

✍ Scribed by Dale L. Boger; Wenying Chai; Rachel S. Ozer; Carl-Magnus Andersson

• Publisher: Elsevier Science
• Year: 1997
• Tongue: English
• Weight: 321 KB
• Volume: 7
• Category: Article
• ISSN: 0960-894X
• DOI: 10.1016/s0960-894x(97)00043-7

✦ Synopsis

The preparation of C2-symmetric and unsymmetric chemical libraries by solution-phase techniques including the use of the olefin metathesis reaction to join and combinatorially randomize the length of a linking tether is detailed.