Solution and Colour Stability of the Bark Extract of Bridelia ferruginea Benth

✍ Scribed by Lara O. Orafidiya; A. Lamikanra; Ifeoma D. Akueme

• Book ID: 101286405
• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 308 KB
• Volume: 10
• Category: Article
• ISSN: 0951-418X
• DOI: 10.1002/(sici)1099-1573(199605)10:3<266::aid-ptr815>3.0.co;2-i

✦ Synopsis

A solvent system consisting of water: propylene glycol: ethanol (2:2:1) was found suitable for diluting the ethanol bark extract and for reconstituting the freeze-dried extract of Bridelia ferruginea Benth for preparation of a gargle formulation. Such solutions remained clear when subjected to high storage temperatures and eight freezethaw cycles. The wine colour of Bridelia bark extract solution darkened on storage. Darkening was accelerated by heat while light had minimal effect. Inclusion of certain antioxidants-sodium metabisulphite, ascorbic acid and citric acid, reduced the colour change. Heating the freeze-dried extract at 115OC for 4 h and at 13OOC for at least 1 h arrested the colour change. When lime juice was added to the solution of the heated powder, the colour of the resulting solution became unstable implicating a pII effect on colour stability. The colour of bottle and use of carton for storage had no appreciable effect on colour stability.