Solute focusing in flow-injection systems: effect of solute capacity factor and position of solute-focusing column

✍ Scribed by Beverly F. Johnson; James Bramlage; John G. Dorsey

• Publisher: Elsevier Science
• Year: 1991
• Tongue: English
• Weight: 649 KB
• Volume: 255
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(91)85097-c

✦ Synopsis

Solute focusing m flow-mJectlon analysis has tradtmnally been performed for lomc solutes and with a change m tamer stream used to cause elunon of the solute Further mvestlgatfions of the use of reversed-phase chromatographic matenals as a solute-focusmg sorbent for non-Iomc solutes are presented By m~ectmg the solute III a chromatograplucally weaker solvent than the tamer stream, real-tnne solute focusmg occurs, and no change m tamer stream or second m]ection 1s requved The effect of the chromatograpluc capacity factor and the location of the focusmg devxe m the flow mamfold are both unportant conslderatmns for attaming the maxnnum enhancement m sensltitmty and concentration lmuts of detectmn Keywords Flow system, hquid chromatography, Capacxty factor, Solute focusmg