Objective. B lymphocytes accumulate in the inflamed joints of patients with rheumatoid arthritis (RA) and are responsible for production of high amounts of (auto)-antibodies. The aim of this study was to determine the capacity of fibroblast-like synoviocytes (FLS) to contribute to the accumulation o
β¦ LIBER β¦
Soluble vascular cell adhesion molecule 1 mediation of monocyte chemotaxis in rheumatoid arthritis
β Scribed by Michihide Tokuhira; Shigeru Hosaka; Michael V. Volin; G. Kenneth Haines III; Kenneth J. Katschke Jr.; Soyun Kim; Alisa E. Koch
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 856 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0004-3591
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## Abstract ## Objective To investigate the roles of MAPKs and NFβΞΊB in tumor necrosis factor Ξ± (TNFΞ±)βinduced expression of vascular cell adhesion molecule 1 (VCAMβ1) in human rheumatoid arthritis synovial fibroblasts (RASFs). ## Methods Human RASFs were isolated from synovial tissue obtained f
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