Soluble Receptor Activator of Nuclear Factor-κB Ligand (sRANKL)/Osteoprotegerin Balance in Ageing and Age-Associated Diseases
✍ Scribed by Lia Pulsatelli; Paolo Dolzani; Tania Silvestri; Paolo Caraceni; Andrea Facchini; Giovanni Ravaglia; Carlo Salvarani; Riccardo Melicòni; Erminia Mariani
- Book ID
- 111573031
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 112 KB
- Volume
- 5
- Category
- Article
- ISSN
- 1389-5729
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## Abstract Earlier reports showed that the balance between receptor activator of nuclear factor‐κB ligand (RANKL) and its decoy‐receptor osteoprotegerin (OPG) plays an important role in the pathogenesis of metastatic osteolysis induced by neuroblastoma cells. In this study, we investigated whether
## Background: The current review summarizes the roles of the ligand, receptor activator of nuclear factor-kappab ligand (rankl), its receptor, receptor activator of nuclear factor-kappab (rank), and its decoy receptor, osteoprotegerin (opg), on osteoclast biology and bone resorption. furthermore,