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Soluble pool of Aβ amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease

✍ Scribed by Catriona A. McLean; Robert A. Cherny; Fiona W. Fraser; Stephanie J. Fuller; Margaret J. Smith; Konrad Vbeyreuther; Ashley I. Bush; Colin L. Masters


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
458 KB
Volume
46
Category
Article
ISSN
0364-5134

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## Abstract The amyloid β‐protein is a 39‐42 amino acid peptide that is deposited in senile plaques and in cerebral vessel walls in individuals with Alzheimer's disease, Down's syndrome, hereditary cerebral hemorrhage with amyloidosis–Dutch type (HCHW A‐D), and, to a much lesser extent, normal agin