𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Soluble poly(ethylene glycol) supported efficient synthesis of 2,5-disubstituted 1,3,4-oxadiazoles and 1,3,4-thiadiazoles

✍ Scribed by Zheng Li; Jingya Yang; Junke Wang; Xicun Wang

Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
112 KB
Volume
17
Category
Article
ISSN
1042-7163

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

An efficient soluble poly(ethylene glycol) (PEG) supported liquid‐phase parallel synthetic method for 2,5‐disubstituted 1,3,4‐oxadiazoles and 1,3,4‐thiadiazoles is described. 2‐Aryl‐5‐(4′‐methoxycarbonylphenoxymethyl)‐1,3,4‐oxadiazoles and 2‐aryloxymethyl‐5‐(4′‐methoxycarbonylphenoxyacetamido)‐1,3,4‐thiadiazoles are synthesized in high yield and high purity using this polymer supported strategy. © 2006 Wiley Periodicals, Inc. Heteroatom Chem 17:664–669, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20253

📜 SIMILAR VOLUMES

Synthesis of pyridazinone-substituted 1,
Synthesis of pyridazinone-substituted 1,3,4-thiadiazoles, -1,3,4-oxadiazoles and -1,2,4-triazoles
✍ Xiajuan Zou; Guiyu Jin 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 32 KB

## Abstract Several 1‐(1‐aryl‐1,4‐dihydro‐3‐carboxy‐6‐methylpyridazin‐4‐one)‐4‐aryl thio‐semicarbazides and their corresponding oxadiazole, thiadiazole and triazole derivatives were prepared and characterized by their spectral data. The preliminary biological tests showed that some new compounds ex

Synthesis of nonsymmetrically 3,4-disubs
Synthesis of nonsymmetrically 3,4-disubstituted 1,2,5-thiadiazole dioxides
✍ Ana Martinez; Ana Castro; Vicente J. Arán; Ignacio Cardelús; Jesús Llenas; José 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 270 KB

## Abstract A synthetic pathway for obtaining arylamino, alkylamino 3,4‐disubstituted 1,2,5‐thiadiazole dioxide derivatives has been developed. This methodology could be applied to obtain potential biologically active molecules.