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Soluble HLA-G generated by proteolytic shedding inhibits NK-mediated cell lysis

โœ Scribed by Gyu Man Park; Sunray Lee; Boyoun Park; Eunkyung Kim; Jinwook Shin; Kwangmin Cho; Kwangseog Ahn


Book ID
116287654
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
216 KB
Volume
313
Category
Article
ISSN
0006-291X

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MICA triggering signal for NK cell tumor
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## Abstract MICA, a highly glycosylated membraneโ€anchored cellโ€“surface MHC Class Iโ€related chain, has recently been reported to activate NK cell cytolytic responses in epithelial tumors. Tumor cells may escape from NK lysis by counteracting NK cytotoxicity activating signals with inhibitory ones. A