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Soluble Guanylate Cyclase from Bovine Lung: Activation with Nitric Oxide and Carbon Monoxide and Spectral Characterization of the Ferrous and Ferric States

โœ Scribed by Stone, James R.; Marletta, Michael A.


Book ID
121003747
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
1022 KB
Volume
33
Category
Article
ISSN
0006-2960

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Synergistic activation of soluble guanyl
โœ James R. Stones; Michael A. Marletta ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 880 KB

## Background: Nitric oxide (.no) is used in biology as both an intercellular signaling agent and a cytotoxic agent. in signaling, submicromolar quantities of .no stimulate the soluble isoform of guanylate cyclase (sgc) in the receptor cell. .no increases the vmax of this heterodimeric hemoprotein