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Soluble Fas (APO-1/CD95) Isoform in Adult T-Cell Leukemia

✍ Scribed by Kamihira, Shimeru; Yamada, Yasuaki

Book ID
120362681
Publisher
Informa plc
Year
2001
Tongue
English
Weight
840 KB
Volume
41
Category
Article
ISSN
1042-8194

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Fas, also designated as Apo-1 and CD95, is a cell membrane receptor (mFas) involved in apoptotic cell death. A soluble form (sFas) lacking the transmembrane domain due to alternative splicing has been isolated. Abnormal expression of sFas and mFas is likely to be involved in lymphoproliferative diso

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