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Soluble and insoluble nickel compounds induce DNA repair synthesis in cultured mammalian cells☆

✍ Scribed by Robison, Steven H.; Cantoni, Orazio; Heck, J.Daniel; Costa, Max

Book ID: 122592976
Publisher: Elsevier Science
Year: 1983
Tongue: English
Weight: 507 KB
Volume: 17
Category: Article
ISSN: 0304-3835
DOI: 10.1016/0304-3835(83)90164-7

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## Abstract Nickel compounds are well known human and animal carcinogens, but the carcinogenic potential depends largely on the actual species. Within the present study, water soluble nickel chloride and poorly water soluble nickel oxide were compared with respect to uptake, intracellular distribut