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Solubility profiles for antipyrine and aminopyrine in hydroalcoholic solutions

✍ Scribed by Anthony N. Paruta

Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
441 KB
Volume
56
Category
Article
ISSN
0022-3549

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Correlation between in vitro dissolution
Correlation between in vitro dissolution profiles from enteric-coated dosage forms and in vivo absorption in rats for high-solubility and high-permeability model drugs
✍ Shinji Sakuma; Ryoko Ogura; Yoshie Masaoka; Makoto Kataoka; FumiΓ© K. Tanno; Hiro πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 161 KB πŸ‘ 1 views

We examined the in vitro dissolution-in vivo absorption correlation (IVIVC) for enteric-coated granules containing theophylline, antipyrine or acetaminophen as model drugs with high solubility and high permeability. More than 85% of each drug was released from granules coated with hypromellose aceta