Solubility of carbon dioxide in lipid bilayer membranes and organic solvents

✍ Scribed by S.A. Simon; John Gutknecht

• Book ID: 115724525
• Publisher: Elsevier Science
• Year: 1980
• Tongue: English
• Weight: 401 KB
• Volume: 596
• Category: Article
• ISSN: 0005-2736
• DOI: 10.1016/0005-2736(80)90122-4

✦ Synopsis

Partition coefficients of carbon dioxide into lipid bilayers (liposomes) and organic solvents were measured as a function of temperature. The molar partition coefficient of CO2 into liposomes of egg lecithin at 25°C was 0.95 (ml CO2/ml lipid)/(ml CO2/ml saline). The addition of an equimolar amount of cholesterol to the egg lecithin decreased the partition coefficient by about 25%. The partition coefficients for CO2 into liposomes at 25°C were lower than the partition coefficients into octanol (1.3), hexadecane (1.5) and olive oil (1.7). The results are discussed in terms of the solubility<liffusion model of non~lectrolyte transport through lipid bilayer membranes.