Solubility as a criterion of purity

✍ Scribed by Thorp, D.

• Publisher: Wiley (John Wiley & Sons)
• Year: 1946
• Weight: 635 KB
• Volume: 65
• Category: Article
• ISSN: 0368-4075
• DOI: 10.1002/jctb.5000651215

✦ Synopsis

Abstract

A method for the determination of the purity of a compound by means of a series of solubility determinations (described in the case of one impurity by Northrop and Kunitz^1^) has been shown to give

The number of main impurities present;

the percentage of each impurity;

the solubility of the compound;

the solubilities of the impurities.

The method which may prove very useful, especially in cases where the probable impurities are related com pounds, e.g., other members of a homologous series, has been applied with success to DDT (Dichloro‐diphenyl‐trichloroethane) and to 22′, 44′ 66′ NN′ oetachloro‐diphenyl‐urea.