Solid-state IR–LD spectroscopic and theoretical analysis of glycine-containing peptides and their hydrochlorides

✍ Scribed by Bojidarka B. Ivanova; Tsonko Kolev; Sonya Y. Zareva

• Publisher: Wiley (John Wiley & Sons)
• Year: 2006
• Tongue: English
• Weight: 423 KB
• Volume: 82
• Category: Article
• ISSN: 0006-3525
• DOI: 10.1002/bip.20512

✦ Synopsis

Abstract

As part of an investigation on the coordination ability of peptides, structural analyses of the solid di‐, tri, and tetrapeptides glycyl‐glycine (GG), glycyl‐glycyl‐glycine (GGG), glycyl‐glycyl‐glycyl‐glycine (GGGG), and their protonated hydrochlorides glycyl‐glycine·HCl (GGH), glycyl‐glycyl‐glycine·HCl (GGGH), and glycyl‐glycyl‐glycyl‐glycine·HCl (GGGGH) have been carried out. The quantum chemical calculations (Hartree‐Fock/6‐31++G**) and linear–dichroic infrared (IR–LD) spectroscopy predict a near to linear structure of the pure ligands, but the experimental IR–LD data are in accordance with a cross‐linked disposition of amide fragments in the protonated forms. © 2006 Wiley Periodicals, Inc. Biopolymers 82:587–596, 2006

This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at [email protected]