𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Solid-phase synthesis of sulfamides

✍ Scribed by Cristina Esteve; Bernat Vidal

Book ID
104232367
Publisher
Elsevier Science
Year
2002
Tongue
French
Weight
58 KB
Volume
43
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis

A straightforward synthesis of diversely substituted sulfamides is described. The reaction of sulfamoylating agent 1 with solid-phase bound amines to give polymer bound BOC substituted sulfamides is described. Further N-alkylation is achieved under Mitsunobu conditions. Simultaneous deprotection and cleavage of the products leads to unsymmetrically substituted sulfamides.

πŸ“œ SIMILAR VOLUMES

Synthesis of new heterocyclic sulfamides
Synthesis of new heterocyclic sulfamides
✍ Galina A. Gazieva; Angelina N. Kravchenko; Konstantin Yu. Chegaev; Yuri A. Strel πŸ“‚ Article πŸ“… 2000 πŸ› Royal Society of Chemistry 🌐 English βš– 64 KB
Solid-phase synthesis
Solid-phase synthesis
✍ Robert C. Sheppard πŸ“‚ Article πŸ“… 1993 πŸ› Elsevier Science 🌐 English βš– 332 KB
Solid-Phase Synthesis
Solid-Phase Synthesis
✍ Andrea Missio πŸ“‚ Article πŸ“… 2006 πŸ› John Wiley and Sons βš– 8 KB πŸ‘ 1 views
General synthesis of n-membered cyclic s
General synthesis of n-membered cyclic sulfamides
✍ Zine RΓ©gaı̈nia; Jean-Yves Winum; Fatma-Zohra Smaine; Loic Toupet; Nour-Eddine Ao πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 143 KB

A general method for the synthesis of n-membered cyclic sulfamides (cyclosulfamides) is described. An application to the synthesis of constrained peptidal cyclic sulfamide is illustrated.