Solid phase synthesis of bifunctional antibodies
โ Scribed by Binodh S. DeSilva; George S. Wilson
- Book ID
- 113181796
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 973 KB
- Volume
- 188
- Category
- Article
- ISSN
- 0022-1759
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๐ SIMILAR VOLUMES
## Abstract Biotinylation is an established method of labeling antibody molecules for several applications in life science research. Antibody functional groups such as amines, __cis__ hydroxyls in carbohydrates or sulfhydryls may be modified with a variety of biotinylation reagents. Solutionโbased
## Abstract The use of the fluorescent bifunctional compounds 7โaminoโ4โcoumarinylโacetic acid **1**, 7โhydroxyโ4โcoumarinylโacetic acid **2** and ethyl 7โaminoโ4โcoumarinylโacetate **3** in solution and solid phase synthesis of fluorogenic enzyme substrates was examined. The intramolecularly quenc