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Solid phase synthesis of 2,4-disubstituted pyridine and tetrahydropyridine derivatives: Resin activation/capture approach/REACAP technology

✍ Scribed by Chixu Chen; Benito Munoz

Publisher: Elsevier Science
Year: 1998
Tongue: French
Weight: 220 KB
Volume: 39
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(98)00533-4

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✦ Synopsis

The resin-bound ¢lihydropyridone scaffold generated using the Resin Activation/Capture Approach (REACAP) Technology was further elaborated to afford 2,4-disubstituted pyridine and tatrahydropyridine derivatives. This process car be envisaged as the functionalization of pyridine analogues on solid support by a tracalees linker approach.

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