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Solid-Phase Synthesis of 1,3,6-Trisubstituted-1 H -thiazolo[4,5- c ][1,2]thiazin-4(3 H )one-2,2-dioxide Derivatives using Traceless Linker

✍ Scribed by Lee, Taeho; Park, Ji-Hoon; Jeon, Moon-Kook; Gong, Young-Dae


Book ID
120089404
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
536 KB
Volume
11
Category
Article
ISSN
1520-4766

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Synthesis of 1-methyl-7-(trifluoromethyl
✍ Frank T. Coppo; Maged M. Fawzi πŸ“‚ Article πŸ“… 1998 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 244 KB

## Abstract The reaction of methyl 2‐bromo‐6‐(trifluoromethyl)‐3‐pyridinecarboxylate (1) with methanesulfonamide gave methyl 2‐[(methylsulfonyl)amino]‐6‐(trifluoromethyl)‐3‐pyridine‐carboxylate (2). Alkylation of compound 2 with methyl iodide followed by cyclization of the resulting methyl 2‐[methy