Solid-phase synthesis and evaluation of TAR RNA targeted β-carboline–nucleoside conjugates
✍ Scribed by Zhao, Peng; Jin, Hong-Wei; Yang, Zhen-Jun; Zhang, Liang-Ren; Zhang, Li-He
- Book ID
- 118738611
- Publisher
- Royal Society of Chemistry
- Year
- 2008
- Tongue
- English
- Weight
- 490 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1477-0520
- DOI
- 10.1039/B809598A
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📜 SIMILAR VOLUMES
## Abstract Dipeptide‐conjugated nucleosides were efficiently synthesized from the intermediates of 3′‐amino‐3′‐deoxy‐nucleosides by using the solid‐phase synthetic strategy with HOBt/HBTU (1‐hydroxy‐1__H__‐benzotriazole/2‐(1__H__‐benzotriazol‐1‐yl)‐1,1,3,3‐tetramethyluronium hexafluoroborate) as t
## Abstract For Abstract see ChemInform Abstract in Full Text.
The parallel synthesis of new fused tetra, penta and hexacyclic b-carbolines via the functionalization of resin-bound tetrahydro-b-carboline derivatives is described. Reduction of the amide bonds and/or nitro group is the key step in the formation of different described fused heterocycles.