Solid-phase stereoselective synthesis of oligonucleoside phosphorothioates: The nucleoside bicyclic oxazaphospholidines as novel synthons

✍ Scribed by Radhakrishnan P Iyer; Mao-Jun Guo; Dong Yu; Sudhir Agrawal

• Book ID: 104259082
• Publisher: Elsevier Science
• Year: 1998
• Tongue: French
• Weight: 219 KB
• Volume: 39
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)00380-3

✦ Synopsis

The nucleoside bicylic oxazaphospholidine derived from L-, or D-prolinol is a novel synthon with potential for solid-phase stereoselective synthesis of oligonucleoside phosphorothioates.