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Solid-Phase Peptide Synthesis in Water Using Microwave-Assisted Heating

✍ Scribed by Galanis, Athanassios S.; Albericio, Fernando; Grøtli, Morten


Book ID
118209561
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
203 KB
Volume
11
Category
Article
ISSN
1523-7060

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Microwave-assisted Boc-solid phase pepti
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## Abstract In this study we describe the first protocols for the synthesis of cystine‐rich peptides in the presence of microwave radiation with Boc‐solid phase peptide synthesis (SPPS). This method is exemplified for macrocyclic peptides known as cyclotides, which comprise ∼30 amino acids and inco