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Solid phase extraction on microfluidic devices

✍ Scribed by Jörg P. Kutter; Stephen C. Jacobson; J. Michael Ramsey

Publisher
John Wiley and Sons
Year
2000
Tongue
English
Weight
85 KB
Volume
12
Category
Article
ISSN
1040-7685

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✦ Synopsis

A microfabricated device with C18-coated channels was used to demonstrate on-chip solid phase extraction. Sample solutions containing a neutral dye were enriched and eluted in less than 4 min. Distinct elution peaks with good signal-to-noise ratios were obtained even for highly dilute samples. The gain in concentration estimated from the enrichment and elution volumes was 80-fold.

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Sample purification on a microfluidic de
Sample purification on a microfluidic device
✍ Tim Footz; Sybille Wunsam; Stephen Kulak; H. John Crabtree; D. Moira Glerum; Chr 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 654 KB

## Sample purification on a microfluidic device Sample preparation has long been recognized as a significant barrier to the implementation of macroscopic protocols on microfabricated devices. Macroscopically, such tasks as removing salts, primers and other contaminants are performed by methods inv