Solid-phase extraction of matrine and oxymatrine from Sophora Flavescens Ait using amino-imidazolium polymer

✍ Scribed by Wentao Bi; Minglei Tian; Kyung Ho Row

• Book ID: 102444836
• Publisher: John Wiley and Sons
• Year: 2010
• Tongue: English
• Weight: 221 KB
• Volume: 33
• Category: Article
• ISSN: 1615-9306
• DOI: 10.1002/jssc.200900835

✦ Synopsis

Abstract

A new, polymer‐confined, ionic liquid sorbent was developed by a process involving polymerization and modification. The obtained particles were successfully used as a special sorbent in SPE process to isolate matrine and oxymatrine from Sophora Flavescens Ait. Different washing and elution solvents, such as ethanol, methanol, acetonitrile and methanol/triethylamine (90:10, v/v), were evaluated. Compared with the C~18~ and NH~2~ sorbents, the amino‐imidazolium polymer sorbent exhibited higher selectivity. Quantitative analysis was carried out by using a C~18~ column. The two compounds exhibited good linearity from 5×10^−3^ to 0.50 mg/mL (r^2^>0.99). The bound amounts between target compounds and proteins were obtained by this sorbent. After three recycles of amino‐imidazolium polymer, the extract amounts of the target compounds were not significantly decreased.