Solid and cystic pancreatic tumors. Clinical, histochemical, and electron microscopic features in ten cases

✍ Scribed by Peter Stömmer; Joachim Kraus; Manfred Stolte; Josef Giedl

• Publisher: John Wiley and Sons
• Year: 1991
• Tongue: English
• Weight: 1011 KB
• Volume: 67
• Category: Article
• ISSN: 0008-543X
• DOI: 10.1002/1097-0142(19910315)67:6<1635::aid-cncr2820670627>3.0.co;2-m

✦ Synopsis

Ten cases of the rare solid and cystic pancreatic tumors are presented. All except one occurred in young women (mean age, 25 +/- 9.2 years). The large neoplasms were evenly distributed across the pancreas; in one case, metastasis occurred; all other cases were free from disease after complete resection. Histologic hallmarks of solid and cystic neoplasms were papillary growth, large intracytoplasmic granules, and immunoreactivity with alpha 1-antitrypsin, alpha 1-antichymotrypsin, phospholipase A2, and neuroendocrine markers (neuron-specific enolase [NSE], synaptophysin). This suggests both endocrine as well as exocrine differentiation.