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Solamargine induces apoptosis associated with p53 transcription-dependent and transcription-independent pathways in human osteosarcoma U2OS cells

โœ Scribed by Xia Li; Ying Zhao; William K.K. Wu; Shanshan Liu; Min Cui; Hongxiang Lou


Book ID
116719925
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
555 KB
Volume
88
Category
Article
ISSN
0024-3205

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## Abstract Kaempferol is a natural flavonoid. Previous studies have reported that kaempferol has antiโ€proliferation activities and induces apoptosis in many cancer cell lines. However, there are no reports on human osteosarcoma. In this study, we investigate the antiโ€cancer effects and molecular m