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Sokolsky-Papkov M, Golovanevski L, Domb A, Weiniger C. 2010. Poly(d,l:lactic–acid-castor oil) 3:7–bupivacaine formulation: Reducing burst effect prolongs efficacy in vivo. J Pharm Sci 99:2732–2738.

✍ Scribed by Marina Sokolsky-Papkov; Ludmila Golovanevski; Abraham J. Domb; Carolyn F. Weiniger

Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 30 KB
Volume: 101
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.23011

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Poly(DL:lactic acid-castor oil) 3:7-bupi

Poly(DL:lactic acid-castor oil) 3:7-bupivacaine formulation: Reducing burst effect prolongs efficacy in vivo

✍ Marina Sokolsky-Papkov; Ludmila Golovanevski; Abraham J. Domb; Carolyn F. Weinig 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB

Prolonged analgesia may be achieved using a single injection of slow-release local anesthetic formulation. The study objective was to improve the efficacy of a previously reported formulation comprising 10% bupivacaine in poly(DL:lactic acid co castor oil) 3:7. The polymer was loaded with 15% bupiva