## Abstract ## BACKGROUND Prognostic factors for metastasis in soft tissue sarcoma govern decisions regarding adjuvant treatment. However, the significance of initial tumorโrelated prognostic factors over time is largely unknown. ## METHODS The current study included 338 patients with malignant
Soft tissue sarcomas of the skull base: Time for a new paradigm
โ Scribed by Franco DeMonte
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 38 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
โฆ Synopsis
Wide surgical resection with negative margins remains the treatment of choice for soft tissue sarcomas of the head and neck and skull base. There is Level 1 evidence to support the addition of radiation to surgical resection for extremity soft tissue sarcoma, but its use in head and neck and skull base tumors is less well established, although it probably is worthwhile. The role of traditional chemotherapy, if any, probably is small, and newer agents need to be assessed under controlled conditions to identify benefit.
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## Abstract ## BACKGROUND: In soft tissue sarcoma, better distinction of highโrisk and lowโrisk patients is needed to individualize treatment and improve survival. Prognostic systems used in clinical practice identify highโrisk patients based on various factors, including age, tumor size and depth
## Abstract ## BACKGROUND. The benefit of chemotherapy in the treatment of primary softโtissue sarcoma (STS) is controversial. To the authors' knowledge, few studies to date have examined the effect of chemotherapy in patients undergoing pulmonary resection for metastatic STS of the extremity. ##