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Soft tissue calcification induced by iron complexes

โœ Scribed by Leopold J. Anghileri


Book ID
104710200
Publisher
Springer
Year
1992
Tongue
English
Weight
143 KB
Volume
51
Category
Article
ISSN
1432-0827

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โœฆ Synopsis


Complexed iron (III) induces a local calcification of soft tissues in mice that is strongly dependent upon the nature of the complexing molecule. Ferric lactate is much more effective in inducing calcification than iron dextran.


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โœ Hui, Mizhou ;Tenenbaum, Howard C. ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 201 KB

Tissue nonspecific alkaline phosphatase (AP) plays a well-known role in bone mineralization. This role was first suggested by a human AP deficiency disease, hypophosphatasia. Further studies with AP gene knockout mice have also suggested a role for AP in mineralization. However, AP is also expressed