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Soft-Pulsed Aluminum-27 Quadrupolar Central Transition NMR Studies of Ovotransferrin

✍ Scribed by James M. Aramini; Markus W. Germann; Hans J. Vogel


Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
123 KB
Volume
129
Category
Article
ISSN
1090-7807

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✦ Synopsis


We have employed soft (Gaussian) pulses to examine 27Al NMR signals arising from Al3+ bound to ovotransferrin. In addition to enhancing the general detectability of 27Al signals from a practical standpoint, this technique makes it possible to invert the central component of the protein-bound 27Al signals, providing a route for, to our knowledge, the first inversion-recovery measurements on such systems. The suitability of this approach for gaining insights into the nature of metal ion binding sites in large metalloproteins is critically assessed. Copyright 1997 Academic Press. Copyright 1997Academic Press