Soft Probes for Bio-electrochemical Imaging

✍ Scribed by Tzu-En Lin

Publisher: Springer International Publishing
Year: 2019
Tongue: English
Leaves: 136
Series: Springer Theses
Edition: 1st ed.
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This book discusses the development of various reliable scanning electrochemical microscopy (SECM) imaging techniques for studying the distribution of biomarkers and nanomaterials in thin and thick animal samples, plant antioxidant (AO) defense systems, as well as human melanoma. The authors demonstrate that SECM could improve the diagnosis and understanding of different melanoma stages on the basis of highly resolved maps of the tyrosinase distribution. Tyrosinase is the key enzyme involved in fruit maturation and is a biomarker for melanoma. As such the book presents various tyrosinase SECM detection strategies developed for the analysis of the spatial distribution of tyrosinase in melanoma and in banana samples. It describes the first imaging of the redox active proteins within the entire mouse heart with an SECM system using a spider probe composed of eight independent microelectrodes. Further, it investigates distributions of injected graphene nanoribbons (GONRs) for drug delivery by Soft-Probe-SECM. Lastly, the book outlines a non-invasive electrochemical strategy for mapping the AO activity of apple peel using Soft-Probe-SECM.

✦ Table of Contents

Front Matter ....Pages i-xxi
Introduction (Tzu-En Lin)....Pages 1-24
Experimental Part (Tzu-En Lin)....Pages 25-36
Multiple SECM Mapping of Tyrosinase in Micro-contact Printed Fruit Samples on Polyvinylidene Fluoride Membrane (Tzu-En Lin)....Pages 37-52
Monitoring Tyrosinase Expression in Non-metastatic and Metastatic Melanoma Tissues by SECM (Tzu-En Lin)....Pages 53-62
From Tissues to Organs: Soft Electrochemical Probes for Scanning Human and Animal Tissues (Tzu-En Lin)....Pages 63-85
Imaging the Distribution of Graphene Oxide Nanoribbons in Mice Livers by Soft Probe SECM (Tzu-En Lin)....Pages 87-100
Mapping the Antioxidant Activity of Apple Peels with Soft Probe Scanning Electrochemical Microscopy (Tzu-En Lin)....Pages 101-116
General Conclusions and Future Perspectives (Tzu-En Lin)....Pages 117-120

✦ Subjects

Chemistry; Analytical Chemistry; Cancer Research; Spectroscopy and Microscopy; Electrochemistry; Biomedical Engineering; Food Science

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