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Sodium salicylate enhances the expression of cyclooxygenase-2 in endotoxin-stimulated human mononuclear cells

✍ Scribed by Rainer Amann; Tamara Egger; Rufina Schuligoi; Akos Heinemann; Bernhard A Peskar


Book ID
114014415
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
134 KB
Volume
433
Category
Article
ISSN
0014-2999

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Cyclooxygenase (COX)-2 is one of the rate-limiting enzymes in the conversion of arachidonic acid to prostaglandins and other eicosanoids. Recent studies have shown enhanced expression of COX-2 in cancer cells of several tissues. We investigated the expression of COX-2 and prostaglandin (PG) E 2 prod