Sodium perborate - a cheap and effective reagent for the oxidation of anilines and sulphides

✍ Scribed by Alexander McKillop; Jonathan A. Tarbin

• Publisher: Elsevier Science
• Year: 1983
• Tongue: French
• Weight: 180 KB
• Volume: 24
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(00)81693-7

✦ Synopsis

Sodium perborate in acetic acid is an effective reagent for the oxidation of anilines to the corresponding nitroarenes; it is also highly effective for the oxidation of sulphides to either sulphoxides or sulphones.

Oxidation is a fundamental process in organic chemistry and the introduction of new reagents and the modification of existing ones is a continuous challenge.

Reagents are now available for almost every conceivable type of oxidation, but in very many instances there are disadvantages associated with their use: high cost, difficulty in handling, lack of sensitivity, toxicity, instability, etc. Sodium perborate, the formula of which is almost invariably given as NaBOg.nH20 (n = l-4), is in fact the heterocycle 1,' and is a very 1091 (1980).