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Sodium nitroprusside inhibits glucose-induced insulin release by activating ATP-sensitive K+ channels

✍ Scribed by M.-H. Antoine; M. Hermann; A. Herchuelz; P. Lebrun


Book ID
119121862
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
730 KB
Volume
1175
Category
Article
ISSN
0167-4889

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Intracellular recordings were made from neurones located in the ventromedial hypothalamic nucleus (VMHN) of slices from rat hypothalamus. These neurones were hyperpolarized on removal of extracellular glucose, resulting in an inhibition of firing, actions which were reversed on the re-introduction o