Sodium-independent taurine binding to brain synaptic membranes
β Scribed by Pirjo Kontro; S. S. Oja
- Book ID
- 104917544
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 295 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0272-4340
No coin nor oath required. For personal study only.
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Taurine is hypothesized to exert its inhibitory neuromodulatory effects, in part, by interaction with the GABA, receptor. Although taurine displaces GABA agonist binding to synaptic membranes, its allosteric effects on the benzodiazepine recognition site of the GABA, receptor complex is unsettled. W
## Abstract [^3^H]βtaurine binding to membranes from different regions from rat brain was studied. Binding to membranes from cerebral cortex and its subcellular fractions, hypothalamus, olfactory bulb and cerebellum was measured. Binding to membranes from dorsal root ganglion was also determined. N