Sodium dependence of the nerve growth factor — regulated hexose uptake in chick embryo ganglionic cells
✍ Scribed by Stephen D. Skaper; Silvio Varon
- Book ID
- 118865119
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 654 KB
- Volume
- 172
- Category
- Article
- ISSN
- 0006-8993
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## Abstract Nerve growth factor (NGF) is required for the growth and development of sensory and sympathetic neurons. Incubation of chick dorsal root ganglionic cells without NGF resulted in a decrease of active (Na^+^, K^+^‐pump‐mediated) K^+^ influx over a period of several hours. Addition of NGF
The uptake of divalent cations and the intracellular concentration of calcium in PC12 cells were studied by flow cytometric analysis using the calcium-sensitive dye, Fluo-3, under a variety of conditions. In particular the actions of nerve growth factor were analyzed. The data show that nerve growth