Sodium Cromoglycate and Nedocromil Sodium in the Therapy of Asthma, a Critical Comparison
β Scribed by M.J. Parnham
- Publisher
- Elsevier
- Year
- 1996
- Tongue
- English
- Weight
- 122 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0952-0600
No coin nor oath required. For personal study only.
β¦ Synopsis
parative studies of the two compounds have been ester carried out. 5,8 Sodium cromoglycate is an inhibitor of ECF release Anti-IgG 4 yes yes 18 the IgE-mediated release of reactive oxygen species Ionophore no no Zymosan no no from human alveolar macrophages, eosinophils and Chemotaxis PAF no yes yes yes 20 platelets. 7 Conflicting data on inhibition by sodium ZAS yes no yes yes cromoglycate of lysosomal enzyme release from FMLP no no yes yes LTB 4 no yes yes yes
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The aim of this study was to compare accurately measured growth over 12 months in asthmatic children treated with either fluticasone propionate (FP) 50 micrograms twice daily (b.i.d.) or sodium cromoglycate (SCG) 20 mg four times daily (q.i.d.). After a 2-week run-in, asthmatic children aged 4-10 ye
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