Sodium channels accumulate at the tips of injured axons
β Scribed by Dr. John D. England; Dr. Fabia Gamboni; Dr. Michele A. Ferguson; Dr. S. Rock Levinson
- Book ID
- 102955384
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 546 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0148-639X
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π SIMILAR VOLUMES
Voltage-gated sodium channels (NaChs) are highly concentrated in the postsynaptic region of the neuromuscular junction, especially in the depths of postsynaptic folds and in the perijunctional region. The formation of the high NaCh density occurs during synapse maturation, approximately 2 weeks afte
The effects of a C 57 type ciguatoxin (CTX-3C) and two types of brevetoxins (PbTx-1 and PbTx-3), known to bind to receptor site 5 of the neuronal voltagedependent Na Ψ channel-protein, were studied on the morphology of living frog myelinated axons using confocal laser scanning microscopy. During the