✦ LIBER ✦

Sodium channel activators: Model of binding inside the pore and a possible mechanism of action

✍ Scribed by Denis B. Tikhonov; Boris S. Zhorov

Book ID: 116465830
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 420 KB
Volume: 579
Category: Article
ISSN: 0014-5793
DOI: 10.1016/j.febslet.2005.07.017

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Antibacterial activity and pore-forming

Antibacterial activity and pore-forming properties of ceratotoxins: a mechanism of action based on the barrel stave model

✍ Yannick Bessin; Nathalie Saint; Laura Marri; Daniela Marchini; Gérard Molle 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 553 KB

Topochemical models for the prediction o

Topochemical models for the prediction of voltage-gated sodium channel binding activity of hydantoins and related non-hydantoins

✍ Meenal Gupta; Anil Kumar Madan 📂 Article 📅 2006 🏛 Springer-Verlag 🌐 English ⚖ 226 KB

Modeling the pore structure of voltage-g

Modeling the pore structure of voltage-gated sodium channels in closed, open, and fast-inactivated conformation reveals details of site 1 toxin and local anesthetic binding

✍ Holger Scheib; Iain McLay; Nicolas Guex; Jeff J. Clare; Frank E. Blaney; Tim J. 📂 Article 📅 2006 🏛 Springer-Verlag 🌐 English ⚖ 339 KB

Solution NMR analysis of the binding mec

Solution NMR analysis of the binding mechanism of DIVS6 model peptides of voltage-gated sodium channels and the lipid soluble alkaloid veratridine

✍ Ai Yoshinaka-Niitsu; Tohru Yamagaki; Masanori Harada; Kazuo Tachibana 📂 Article 📅 2012 🏛 Elsevier Science 🌐 English ⚖ 999 KB

Possible role of slow sodium-calcium cha

Possible role of slow sodium-calcium channels in the mechanism of changes in electrical and mechanical activity of guinea pig heart cells in local anaphylaxis (the isoptine effects)

✍ B. I. Khodorov; E. G. Vornovitskii; V. B. Ignat'eva 📂 Article 📅 1974 🏛 Springer US 🌐 English ⚖ 458 KB

Is the A-ring lactone of brevetoxin PbTX

Is the A-ring lactone of brevetoxin PbTX-3 required for sodium channel orphan receptor binding and activity?

✍ Professor Daniel G. Baden; Kathleen S. Rein; Robert E. Gawley; Gerhard Jeglitsch 📂 Article 📅 1994 🏛 John Wiley and Sons 🌐 English ⚖ 841 KB

Brevetoxin PbTx-3 and non-toxic derivative 4 were investigated for their abilities to bind to the specific brevetoxin receptor site on rat brain synaptosomes and to modulate the normal function of voltage-gated sodium channels as determined by patch clamping of cultured neurons. Compounds 4 and 5 ar